Drs. Shannon Manzi and Gunter Scharer will discuss how to use TPMT and NUDT15 pharmacogenetics (PGx) to guide thiopurines dosing and reduce adverse events. Dr. Sharer will focus on TPMT and NUDT15 testing and how to use the latest Clinical Pharmacogenetics Implementation Consortium (CPIC) guideline to improve thiopurines dosing. Dr. Manzi will share her hands-on experience on developing a team-based precision medicine program to improve patient care and reduce cost of care at Boston Children’s Hospital.
Date/Time: 1:00 pm CDT, Thursday, September 26, 2019
Agenda (55 min):
- PGx of TPMT and NUDT15: the latest Clinical Pharmacogenetic Implementation Consortium (CPIC) guideline, by Dr. Gunter Scharer, MD, PhD — 15 min
- PGx at Boston Children’s Hospital, by Dr. Shannon Manzi, PharmD — 30 min
- Q&A — 5-10 min
Shannon Manzi, PharmD
Dr. Manzi is a clinical pharmacist and has practiced pediatric pharmacy for more than 20 years. She serves as the Director of the Clinical pharmacogenomics Service at Boston Children’s Hospital and is an Assistant Professor of Pediatrics at Harvard Medical School. Dr. Manzi is the member of the Clinical Pharmacogenetics Implementation Consortium (CPIC).
Gunter Scharer, MD, PhD
Dr. Scharer is a board-certified medical geneticist with 15+ years of clinical and laboratory experience. He is a renowned geneticist with deep experience in rare disorders and mitochondrial disease. Dr. Scharer is a member of the CPIC and Pharmacogenomics Research Network (PGRN).
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