Search by Gene or Drug Name

Precision Medicine Experts at RPRDx

Search by Gene or Drug Name

Whole Pharmacogenomics Scan (WPSTM) is the most comprehensive PGx test. Search in the below WPS gene-drug evidence database* to find the gene and drug of your interests.

Due to the large scope of the test, only the gene/drug pairs with CPIC level are shown.

If the genes and drugs you are interested in are not shown in the list, there is a good chance that they are still included in the WPS. Please contact us to determine whether WPS tests the genes you are interested in.

GeneDrug Generic NameDrug Brand Name(s)SpecialtyCPIC GuidelineCPIC LevelPharmGKB Level of EvidencePGx on FDA Label
ABCB1AgomelatineValdoxan, Melitor, ThymanaxPsychiatryA/B3
ABCB1AmaxapineAsendinPsychiatryA/B3
ABCB1AmitriptylineElavilPsychiatryA/B3
ABCB1BupropionWellbutrinPsychiatryA/B3
ABCB1CitalopramCelexaPsychiatryA/B3
ABCB1ClomipramineAnafranilPsychiatryA/B3
ABCB1DesipramineNorpraminPsychiatryA/B3
ABCB1DesvenlafaxinePristiqPsychiatryA/B3
ABCB1DigoxinLanoxin, DigoxCardiovascularC/D2A
ABCB1DoxepinSilenor, Zonalon, PrudoxinPsychiatryA/B3
ABCB1DuloxetineCymbaltaPsychiatryA/B3
ABCB1EscitalopramLexaproPsychiatryA/B3
ABCB1FentanylDuragesic, SublimazeAnalgesic / AnesthesiologyC/D2B
ABCB1FluoxetineProzac, SarafemPsychiatryA/B3
ABCB1FluvoxamineLuvoxPsychiatryA/B3
ABCB1ImipramineTogranilPsychiatryA/B3
ABCB1IronPsychiatryA/B3
ABCB1IsocarboxazidMarplanPsychiatryA/B3
ABCB1L-TryptophanTryptan, AminominePsychiatryA/B3
ABCB1MaprotilineLudiomilPsychiatryA/B3
ABCB1MethadoneDolophine, MethadoseAnalgesic / AnesthesiologyC/D2B
ABCB1MethotrexateRheumatrexOncologyC/D2A
ABCB1MianserinTolvonPsychiatryA/B3
ABCB1MilnacipranIxel, Savella, Dalcipran, ToledominPsychiatryA/B3
ABCB1MinaprineBrantur, CantorPsychiatryA/B3
ABCB1MirtazapineRemeronPsychiatryA/B3
ABCB1MoclobemideAmira, Aurorix, Clobemix, Depnil, ManerixPsychiatryA/B3
ABCB1MorphineKadian, MS ContinAnalgesic / AnesthesiologyC/D2B
ABCB1NefazodoneSerzonePsychiatryA/B3
ABCB1NevirapineViramuneInfectious DiseaseC/D2A
ABCB1NortriptylinePamelorPsychiatryA/B3
ABCB1OndansetronZofranGastroenterologyC/D2A
ABCB1OxycodoneOxycontin, RoxicodoneAnalgesic / AnesthesiologyC/D2B
ABCB1ParoxetinePaxilPsychiatryA/B3
ABCB1PhenelzineNardilPsychiatryA/B3
ABCB1ProtriptylineVivactilPsychiatryA/B3
ABCB1ReboxetineEronaxPsychiatryA/B3
ABCB1SertralineZoloftPsychiatryA/B3
ABCB1SimvastatinZocorCardiovascularC/D2A
ABCB1SunitinibSutentOncologyC/D2B
ABCB1TramadolUltram, ConzipAnalgesic / AnesthesiologyC/D2B
ABCB1TranycypromineParnatePsychiatryA/B3
ABCB1TrazodoneDesyrelPsychiatryA/B3
ABCB1TrimipramineSurmontilPsychiatryA/B3
ABCB1VenlafaxineEffexorPsychiatryA/B3
ABCC4TenofovirVireadInfectious DiseaseD2B
ABCG2RosuvastatinCrestorCardiovascularB2B
ACECaptoprilAcediur, Aceplus, Acepress, Acepril, Alopresin, Apopril, Capoten, Captolane, Captoril, Cesplon, Dilabar, Garranil, Hipertil, Hypertil, Lopirin, Lopril, Tenosbon, Tensobon, TensoprelCardiovascularD2A
ADD1FurosemideLasixInternalD2B
ADD1SpironolactoneAldactoneCardiovascularD2B
ADORA2ACaffeineNo Doz, VivarinDietaryD2B
ADRB2SalbutamolProAir HFA, Proventil HFA, ProAir RespiClickPulmonaryC/D2A
ADRB2SalmeterolSereventPulmonaryC/D2A
ANKK1AmisulprideSolianPsychiatryD2B
ANKK1AripiprazoleAbilify PsychiatryD2B
ANKK1BupropionWellbutrinPsychiatryD3
ANKK1ClozapineClozarilPsychiatryD2B
ANKK1EthanolGeneralD2B
ANKK1HaloperidolHaldol PsychiatryD2B
ANKK1OlanzapineZyprexaPsychiatryD2B
ANKK1PaliperidoneInvegaPsychiatryD2B
ANKK1QuetiapineSeroquelPsychiatryD2B
ANKK1RisperidoneRisperdalPsychiatryD2B
ANKK1ZiprasidoneGeodon PsychiatryD2B
APOEAtorvastatinLipitorCardiovascularD2A
ASS1Valproic AcidValproicNeurologyB
ATICMethotrexateRheumatrexOncologyD2B
BCHESuccinylcholineAnectine, QuelicinAnalgesic / AnesthesiologyC/D3Actionable PGx
C11orf65MetforminFortamet, Glucophase, Glucophase Xr, Glumetza, RiometEndocrinologyD2B
C8orf34IrinotecanCamptosarOncologyD2B
CACNA1S
Gene Information >
DesfluraneSupraneAnalgesic / AnesthesiologyView >A1AActionable PGx
CACNA1S
Gene Information >
EnfluraneEthraneAnalgesic / AnesthesiologyView >A1AActionable PGx
CACNA1S
Gene Information >
HalothaneFluothaneAnalgesic / AnesthesiologyView >A1A
CACNA1S
Gene Information >
IsofluraneForane, TerrellAnalgesic / AnesthesiologyView >A1AActionable PGx
CACNA1S
Gene Information >
MethoxyfluranePenthroxAnalgesic / AnesthesiologyView >A1A
CACNA1S
Gene Information >
SevofluraneUltaneAnalgesic / AnesthesiologyView >A1AActionable PGx
CACNA1S
Gene Information >
SuccinylcholineAnectine, QuelicinAnalgesic / AnesthesiologyView >A1AActionable PGx
CALUWarfarinCoumadin, JantovenAnticoagulant / AntiplateletD2B
CBR3DaunorubicinCerubidineOncologyD2B
CBR3DoxorubicinAdriamycin, RubexOncologyD2B
CBR3EpirubicinEllenceOncologyD2B
CBR3IdarubicinIdamycin PFSOncologyD2B
CBR3MitoxantroneNovantrone, OTN MitoxantroneOncologyD2B
CBR3ValrubicinValstarOncologyD2B
CCHCR1NevirapineViramuneInfectious DiseaseD2B
CES1ClopidogrelPlavixCardiovascularC/D2B
CETPAtorvastatinLipitorCardiovascularD2B
CETPCerivastatinBaycol, LipobayCardiovascularD2B
CETPFluvastatinLescolCardiovascularD2B
CETPLovastatinMevacorCardiovascularD2B
CETPPitavastatinLivaloCardiovascularD2B
CETPPravastatinPravacholCardiovascularD2B
CETPRosuvastatinCrestorCardiovascularD2B
CETPSimvastatinZocorCardiovascularD2B
CFTR
Gene Information >
AtalurenTranslarnaGenetic DiseaseC2A
CFTR
Gene Information >
IvacaftorKalydecoGenetic DiseaseView >A1ATesting required
CHRNA3NicotineNicoderm C-Q, Nicorette, NicotrolPsychiatryD2B
COL22A1SalbutamolProAir HFA, Proventil HFA, ProAir RespiClickPulmonaryD2B
COMTCisplatinPlatinol, Platinol-AQOncologyC/D3
COMTCitalopramCelexaPsychiatryC2B
COMTEscitalopramLexaproPsychiatryC2B
COMTFluoxetineProzac, SarafemPsychiatryC2B
COMTFluvoxamineLuvoxPsychiatryC2B
COMTNicotineNicoderm C-Q, Nicorette, NicotrolPsychiatryC/D2A
COMTParaxetinePaxil, PexevaPsychiatryC2B
COMTSertralineZoloftPsychiatryC2B
COQ2AtorvastatinLipitorCardiovascularD2B
COQ2RosuvastatinCrestorInternalD2B
CPS1Valproic AcidValproicNeurologyB
CRHR1BudesonideEntocort, Uceris, PulmicortGastroenterologyD2B
CRHR1Fluticasone PropionateCutivate, Flonase Allergy ReliefAllergyD2B
CRHR1Fluticasone/SalmeterolAdvairdiskus Diskus, AirDuo RespiClick, Advair HFAPulmonaryD2B
CRHR1TriamcinoloneAristocort A, Cinolar, Kenalog, Pediaderm TA, TriacetDermatologyD2B
CRHR2SalbutamolProAir HFA, Proventil HFA, ProAir RespiClickPulmonaryD2B
CYB5R1MetoclopramideMetozolv ODT, ReglanGastroenterologyDActionable PGx
CYB5R3MetoclopramideMetozolv ODT, ReglanGastroenterologyDActionable PGx
CYP2B6
Gene Information >
EfavirenzSustivaInfectious DiseaseView >A1BActionable PGx
CYP2B6
Gene Information >
MethadoneDolophine, MethadoseAnalgesic / AnesthesiologyB2A
CYP2B6
Gene Information >
NevirapineViramuneInfectious DiseaseB2A
CYP2C19
Gene Information >
AmitriptylineElavilPsychiatryView >A1A
CYP2C19
Gene Information >
BrivaracetamBriviactNeurologyB/C4Actionable PGx
CYP2C19
Gene Information >
CarisoprodolSomaAnalgesic / AnesthesiologyB/C3Actionable PGx
CYP2C19
Gene Information >
CitalopramCelexaPsychiatryView >A1AActionable PGx
CYP2C19
Gene Information >
ClobazamOnfiNeurologyC2AActionable PGx
CYP2C19
Gene Information >
ClomipramineAnafranil, Triamcot, Triderm, ZytopicPsychiatryView >B2A
CYP2C19
Gene Information >
ClopidogrelPlavixAnticoagulant / AntiplateletView >A1AActionable PGx
CYP2C19
Gene Information >
DexlansoprazoleDexilantGastroenterologyBActionable PGx
CYP2C19
Gene Information >
DiazepamValiumPsychiatryC3Actionable PGx
CYP2C19
Gene Information >
DoxepinSilenor, Zonalon, PrudoxinPsychiatryView >B3Actionable PGx
CYP2C19
Gene Information >
EscitalopramLexaproPsychiatryView >A1AActionable PGx
CYP2C19
Gene Information >
EsomeprazoleNexiumGastroenterologyB3Actionable PGx
CYP2C19
Gene Information >
FlibanserinAddyiPsychiatryCActionable PGx
CYP2C19
Gene Information >
ImipramineTofranilPsychiatryView >B2A
CYP2C19
Gene Information >
LansoprazolePrevacidGastroenterologyB2AInformative PGx
CYP2C19
Gene Information >
OmeprazolePrilosecGastroenterologyB2AActionable PGx
CYP2C19
Gene Information >
PantoprazoleProtonixGastroenterologyB3Actionable PGx
CYP2C19
Gene Information >
RabeprazoleAciphexGastroenterologyB2AActionable PGx
CYP2C19
Gene Information >
SertralineZoloftPsychiatryView >B1A
CYP2C19
Gene Information >
TrimipramineSurmontilPsychiatryView >B2A
CYP2C19
Gene Information >
VoriconazoleVfendInfectious DiseaseView >A1AActionable PGx
CYP2C8RosiglitazoneAvandiaEndocrinologyC/D2A
CYP2C9
Gene Information >
AcenocoumarolSintromAnticoagulant / AntiplateletB2A
CYP2C9
Gene Information >
CelecoxibCelebrexAnti-inflammatoryB2AActionable PGx
CYP2C9
Gene Information >
DiclofenacVoltarenAnti-inflammatoryC2A
CYP2C9
Gene Information >
FlibanserinAddyiPsychiatryCActionable PGx
CYP2C9
Gene Information >
FlurbiprofenAnsaidAnti-inflammatoryB/C3Actionable PGx
CYP2C9
Gene Information >
LesinuradZurampicRheumatologyCActionable PGx
CYP2C9
Gene Information >
PhenytoinDilantinNeurologyView >A1AActionable PGx
CYP2C9
Gene Information >
SiponimodMayzentNeurologyATesting required
CYP2C9
Gene Information >
WarfarinCoumadin, JantovenAnticoagulant / AntiplateletView >A1AActionable PGx
CYP2D6
Gene Information >
AmitriptylineElavilPsychiatryView >A1AActionable PGx
CYP2D6
Gene Information >
AripiprazoleAbilifyPsychiatryB3Actionable PGx
CYP2D6
Gene Information >
AtomoxetineStratteraPsychiatryB2AActionable PGx
CYP2D6
Gene Information >
BrexpiprazoleRexultiPsychiatryBActionable PGx
CYP2D6
Gene Information >
CarvedilolCoregCardiovascularC3Actionable PGx
CYP2D6
Gene Information >
CevimelineEvoxacRheumatologyCActionable PGx
CYP2D6
Gene Information >
ClomipramineAnafranilPsychiatryView >B1AActionable PGx
CYP2D6
Gene Information >
ClozapineClozarilPsychiatryCActionable PGx
CYP2D6
Gene Information >
CodeineAnalgesic / AnesthesiologyView >A1AActionable PGx
CYP2D6
Gene Information >
DarifenacinEnablexUrologyCActionable PGx
CYP2D6
Gene Information >
DesipramineNorpraminPsychiatryView >B1AActionable PGx
CYP2D6
Gene Information >
DextromethorphanDelsymPulmonaryB3
CYP2D6
Gene Information >
DolasetronAnzemetGastroenterologyC3
CYP2D6
Gene Information >
DonepezilAriceptNeurologyB/C3Actionable PGx
CYP2D6
Gene Information >
DoxepinSilenor, Zonalon, PrudoxinPsychiatryView >B1AActionable PGx
CYP2D6
Gene Information >
DuloxetineCymbaltaPsychiatryCActionable PGx
CYP2D6
Gene Information >
EliglustatCerdelgaGenetic DiseaseBTesting required
CYP2D6
Gene Information >
FesoterodineToviazUrologyCActionable PGx
CYP2D6
Gene Information >
FlecainideTambocorCardiovascularC2A
CYP2D6
Gene Information >
FlibanserinAddyiPsychiatryCActionable PGx
CYP2D6
Gene Information >
FluoxetineProzac, SarafemPsychiatryC3Informative PGx
CYP2D6
Gene Information >
FluvoxamineLuvoxPsychiatryView >A1AActionable PGx
CYP2D6
Gene Information >
GalantamineRazadyne, Razadyne ERNeurologyD3Informative PGx
CYP2D6
Gene Information >
HaloperidolHaldolPsychiatryC3
CYP2D6
Gene Information >
IloperidoneFanaptPsychiatryB/C3Actionable PGx
CYP2D6
Gene Information >
ImipramineTofranilPsychiatryView >B1AActionable PGx
CYP2D6
Gene Information >
MethylphenidateConcerta, Daytrana, MethylinPsychiatryB4
CYP2D6
Gene Information >
MetoprololLopressorCardiovascularC2AInformative PGx
CYP2D6
Gene Information >
MirtazapineRemeronPsychiatryB2A
CYP2D6
Gene Information >
ModafinilProvigilSleep MedicineCActionable PGx
CYP2D6
Gene Information >
NortriptylinePamelorPsychiatryView >A1AActionable PGx
CYP2D6
Gene Information >
OlanzapineZydisPsychiatryC3
CYP2D6
Gene Information >
OndansetronZofranGastroenterologyView >A1AInformative PGx
CYP2D6
Gene Information >
OxycodoneOxycontin, RoxicodoneAnalgesic / AnesthesiologyA2A
CYP2D6
Gene Information >
PalonosetronAloxiInternalCInformative PGx
CYP2D6
Gene Information >
ParoxetinePaxilPsychiatryView >A1AInformative PGx
CYP2D6
Gene Information >
PerphenazineEtrafonPsychiatryB/CActionable PGx
CYP2D6
Gene Information >
PimozideOrapPsychiatryB4Testing required
CYP2D6
Gene Information >
PropafenoneRythmolCardiovascularC2AActionable PGx
CYP2D6
Gene Information >
PropranololInderalCardiovascularC4Informative PGx
CYP2D6
Gene Information >
ProtriptylineVivactilPsychiatryBActionable PGx
CYP2D6
Gene Information >
QuinidineQuin-GCardiovascularBInformative PGx
CYP2D6
Gene Information >
QuinineQualaquinInfectious DiseaseCActionable PGx
CYP2D6
Gene Information >
RisperidoneRisperdalPsychiatryB2AInformative PGx
CYP2D6
Gene Information >
SertralineZoloftPsychiatryB3
CYP2D6
Gene Information >
TamoxifenSoltamoxOncologyView >A1AActionable PGx
CYP2D6
Gene Information >
TamsulosinFlomaxUrologyCActionable PGx
CYP2D6
Gene Information >
TerbinafineLamisilInfectious DiseaseCInformative PGx
CYP2D6
Gene Information >
TetrabenazineXenazineNeurologyCTesting required
CYP2D6
Gene Information >
Thioridazine MellarilPsychiatryC3Actionable PGx
CYP2D6
Gene Information >
TimololBlocadrenCardiovascularC3
CYP2D6
Gene Information >
TiotropiumSpiriva with HandiHaler, Spiriva RespimatPulmonaryCInformative PGx
CYP2D6
Gene Information >
TolterodineDetrolUrologyC2AActionable PGx
CYP2D6
Gene Information >
TramadolUltram, ConZip, ConzipAnalgesic / AnesthesiologyA1BActionable PGx
CYP2D6
Gene Information >
TrimipramineSurmontilPsychiatryView >B1AActionable PGx
CYP2D6
Gene Information >
TropisetronNavobanGeneralView >A
CYP2D6
Gene Information >
VenlafaxineEffexorPsychiatryB2AActionable PGx
CYP2D6
Gene Information >
VortioxetineTrintellixPsychiatryB3Actionable PGx
CYP2D6
Gene Information >
ZuclopenthixolCisordinol, Clopixol-AcuphasePsychiatryC3
CYP3A4TacrolimusPrografImmunosuppressionC2A
CYP3A5
Gene Information >
AtazanavirReyatazInfectious DiseaseC3
CYP3A5
Gene Information >
CyclosporineGengrafImmunosuppressionC2B
CYP3A5
Gene Information >
MidazolamVersedAnalgesic / AnesthesiologyC3
CYP3A5
Gene Information >
SirolimusRapamuneImmunosuppressionC2A
CYP3A5
Gene Information >
TacrolimusPrografImmunosuppressionView >A1A
CYP4F2
Gene Information >
AcenocoumarolSintromAnticoagulant / AntiplateletB2A
CYP4F2
Gene Information >
PhenprocoumonMarcoumar, Marcumar, FalithromAnticoagulant / AntiplateletB2A
CYP4F2
Gene Information >
WarfarinCoumadin, JantovenAnticoagulant / AntiplateletView >A1A
DPYD
Gene Information >
CapecitabineXelodaOncologyView >A1AActionable PGx
DPYD
Gene Information >
FluorouracilEfudex, Fluoroplex, Carac, Adrucil, TolakOncologyView >A1AActionable PGx
DPYD
Gene Information >
TegafurOncologyView >C1A
DRD2RisperidoneRisperdalPsychiatryC2A
DYNC2H1EtoposideOncologyD2B
DYNC2H1EtoposideToposarOncologyD2B
DYNC2H1Platinum CompoundsOncologyD2B
EGFCetuximabErbituxOncologyD2B
EPHX1CarbamazepineCarbatrolNeurologyD2B
ERCC1Platinum CompoundsOncologyD2B
F5DesogestrelCerazette, MircetteObstetrics & GynecologyC2A
F5EltrombopagPromactaOncologyCActionable PGx
F5EtonogestrelCirclet, Implanon, Nexplanon, NuvaRingObstetrics & GynecologyC2A
F5GestodeneFemodene , MinuletObstetrics & GynecologyC2A
F5LevonorgestrelMirena, Plan B, SkylaObstetrics & GynecologyC2A
F5MedroxyprogesteroneProvera, Depo-Provera, Depo-SubQ provera 104Obstetrics & GynecologyC2A
F5MegestrolMegaceObstetrics & GynecologyC2A
F5NorelgestrominXulane, Ortho EvraObstetrics & GynecologyC2A
F5NorethindroneAygestin, Camila, Errin, Jolivette, LyzaObstetrics & GynecologyC2A
F5NorgestimatePrefest, Prtho-PrefestObstetrics & GynecologyC2A
F5NorgestrelOvretteObstetrics & GynecologyC2A
FCGR3ACetuximabErbituxOncologyD3
FCGR3ARituximabRituxan, TruximaOncologyD2B
FDPSAlendronateFosamax, Binosto, Fosamax Plus DInternalD2B
FDPSClodronateBonefosInternalD2B
FDPSEtidronic AcidInternalD2B
FDPSIbandronateBonivaInternalD2B
FDPSPamidronateArediaInternalD2B
FDPSRisedronateActonel, AtelviaInternalD2B
FDPSTiludronateSkelidInternalD2B
FDPSZoledronateReclastInternalD2B
FKBP5AgomelatineValdoxan, Melitor, ThymanaxPsychiatryD2B
FKBP5AmaxapineAsendinPsychiatryD2B
FKBP5AmitriptylineElavilPsychiatryD2B
FKBP5BupropionWellbutrinPsychiatryD2B
FKBP5CitalopramCelexaPsychiatryD2B
FKBP5ClomipramineAnafranilPsychiatryD2B
FKBP5DesipramineNorpraminPsychiatryD2B
FKBP5DesvenlafaxinePristiqPsychiatryD2B
FKBP5DoxepinSilenor, Zonalon, PrudoxinPsychiatryD2B
FKBP5DuloxetineCymbaltaPsychiatryD2B
FKBP5EscitalopramLexaproPsychiatryD2B
FKBP5FluoxetineProzac, SarafemPsychiatryD2B
FKBP5FluvoxamineLuvoxPsychiatryD2B
FKBP5ImipramineTogranilPsychiatryD2B
FKBP5IronPsychiatryD2B
FKBP5IsocarboxazidMarplanPsychiatryD2B
FKBP5L-TryptophanTryptan, AminominePsychiatryD2B
FKBP5MaprotilineLudiomilPsychiatryD2B
FKBP5MianserinTolvonPsychiatryD2B
FKBP5MilnacipranIxel, Savella, Dalcipran, ToledominPsychiatryD2B
FKBP5MinaprineBrantur, CantorPsychiatryD2B
FKBP5MirtazapineRemeronPsychiatryD2B
FKBP5MoclobemideAmira, Aurorix, Clobemix, Depnil, ManerixPsychiatryD2B
FKBP5NefazodoneSerzonePsychiatryD2B
FKBP5NortriptylinePamelorPsychiatryD2B
FKBP5ParoxetinePaxilPsychiatryD2B
FKBP5PhenelzineNardilPsychiatryD2B
FKBP5ProtriptylineVivactilPsychiatryD2B
FKBP5ReboxetineEronaxPsychiatryD2B
FKBP5SertralineZoloftPsychiatryD2B
FKBP5TranycypromineParnatePsychiatryD2B
FKBP5TrazodoneDesyrelPsychiatryD2B
FKBP5TrimipramineSurmontilPsychiatryD2B
FKBP5VenlafaxineEffexorPsychiatryD2B
FLOT1CarbamazepineCarbatrolNeurologyD
G6PD
Gene Information >
ChloramphenicolChloromycetin, Econochlor, Ocu-ChlorInfectious DiseaseB3
G6PD
Gene Information >
ChloroquineAralenInfectious DiseaseB3Actionable PGx
G6PD
Gene Information >
ChlorpropamideDiabineseEndocrinologyBActionable PGx
G6PD
Gene Information >
CiprofloxacinCetraxal, Ciloxan, Cipro in D5WInfectious DiseaseB4
G6PD
Gene Information >
DabrafenibTafinlarOncologyB/CActionable PGx
G6PD
Gene Information >
DapsoneAczoneInfectious DiseaseB1BActionable PGx
G6PD
Gene Information >
DimercaprolBal in OilGeneralB3
G6PD
Gene Information >
ErythromycinE.E.S.Infectious DiseaseB
G6PD
Gene Information >
GlibenclamideGlynaseEndocrinologyB3Actionable PGx
G6PD
Gene Information >
GlimepirideAmarylEndocrinologyBActionable PGx
G6PD
Gene Information >
GlipizideGlucotrolEndocrinologyBActionable PGx
G6PD
Gene Information >
HydroxychloroquinePlaquenilInfectious DiseaseB
G6PD
Gene Information >
LevofloxacinLevaquinInfectious DiseaseB
G6PD
Gene Information >
LidocaineXylocaineCardiovascularB/C
G6PD
Gene Information >
MafenideSulfamylonInfectious DiseaseBActionable PGx
G6PD
Gene Information >
MefloquineLariamInfectious DiseaseB3
G6PD
Gene Information >
MesalazineCanasa, Apriso, LialdaAnti-inflammatoryB
G6PD
Gene Information >
Methylene BlueProvayBlueGeneralB3Actionable PGx
G6PD
Gene Information >
MoxifloxacinAvalox, Vigamox, MoxezaInfectious DiseaseB
G6PD
Gene Information >
Nalidixic AcidNegGramInfectious DiseaseBActionable PGx
G6PD
Gene Information >
NitrofurantoinMacrobid, Furadantin, MacrodantinInfectious DiseaseB3Actionable PGx
G6PD
Gene Information >
NorfloxacinNoroxinInfectious DiseaseBActionable PGx
G6PD
Gene Information >
PegloticaseKrystexxaInternalB3Testing required
G6PD
Gene Information >
PhenazopyridineAzo-Gesic, Azo-Septic, Baridium, Phenazo 95UronologyB3
G6PD
Gene Information >
PrimaquineInfectious DiseaseB3Testing required
G6PD
Gene Information >
ProbenecidProbalanInternalBActionable PGx
G6PD
Gene Information >
QuinineQualaquinInfectious DiseaseBActionable PGx
G6PD
Gene Information >
RasburicaseElitekOncologyView >A1ATesting required
G6PD
Gene Information >
Sodium NitriteGeneralBActionable PGx
G6PD
Gene Information >
SulfacetamideBleph-10, Klaron, OvaceInfectious DiseaseB
G6PD
Gene Information >
SulfadiazineInfectious DiseaseBActionable PGx
G6PD
Gene Information >
Sulfamethoxazole / TrimethoprimBactrim, Sulfatrim, Bactrim DSInfectious DiseaseB3Actionable PGx
G6PD
Gene Information >
SulfasalazineAzulfidine, Azulfidine EN-tabsRheumatologyB4Actionable PGx
G6PD
Gene Information >
SulfisoxazoleInfectious DiseaseB
G6PD
Gene Information >
TafenoquineKrintafelInfectious DiseaseATesting required
G6PD
Gene Information >
Vitamin CGeneralC
GBAVelaglucerase AlfaVprivGenetic DiseaseBTesting required
GGCXWarfarinCoumadinAnticoagulant / AntiplateletD2B
GNB3SildenafilRevatioPulmonaryD2B
GP1BAAspirinGeneralD2B
GRIK4AgomelatineValdoxan, Melitor, ThymanaxPsychiatryD2B
GRIK4AmaxapineAsendinPsychiatryD2B
GRIK4AmitriptylineElavilPsychiatryD2B
GRIK4BupropionWellbutrinPsychiatryD2B
GRIK4CitalopramCelexaPsychiatryD2B
GRIK4ClomipramineAnafranilPsychiatryD2B
GRIK4DesipramineNorpraminPsychiatryD2B
GRIK4DesvenlafaxinePristiqPsychiatryD2B
GRIK4DoxepinSilenor, Zonalon, PrudoxinPsychiatryD2B
GRIK4DuloxetineCymbaltaPsychiatryD2B
GRIK4EscitalopramLexaproPsychiatryD2B
GRIK4FluoxetineProzac, SarafemPsychiatryD2B
GRIK4FluvoxamineLuvoxPsychiatryD2B
GRIK4ImipramineTogranilPsychiatryD2B
GRIK4IronPsychiatryD2B
GRIK4IsocarboxazidMarplanPsychiatryD2B
GRIK4L-TryptophanTryptan, AminominePsychiatryD2B
GRIK4MaprotilineLudiomilPsychiatryD2B
GRIK4MianserinTolvonPsychiatryD2B
GRIK4MilnacipranIxel, Savella, Dalcipran, ToledominPsychiatryD2B
GRIK4MinaprineBrantur, CantorPsychiatryD2B
GRIK4MirtazapineRemeronPsychiatryD2B
GRIK4MoclobemideAmira, Aurorix, Clobemix, Depnil, ManerixPsychiatryD2B
GRIK4NefazodoneSerzonePsychiatryD2B
GRIK4NortriptylinePamelorPsychiatryD2B
GRIK4ParoxetinePaxilPsychiatryD2B
GRIK4PhenelzineNardilPsychiatryD2B
GRIK4ProtriptylineVivactilPsychiatryD2B
GRIK4ReboxetineEronaxPsychiatryD2B
GRIK4SertralineZoloftPsychiatryD2B
GRIK4TranycypromineParnatePsychiatryD2B
GRIK4TrazodoneDesyrelPsychiatryD2B
GRIK4TrimipramineSurmontilPsychiatryD2B
GRIK4VenlafaxineEffexorPsychiatryD2B
GSTM1CisplatinPlatinol, Platinol-AQOncologyD2B
GSTM1OxaliplatinEloxatinOncologyD2B
GSTP1CyclophosphamideCytoxan, NeosarOncologyC/D2A
GSTP1EpirubicinEllenceOncologyC/D2A
GSTP1FluorouracilEfudex, Fluoroplex, Carac, Adrucil, TolakOncologyC/D2A
GSTP1OxaliplatinEloxatinOncologyC/D2A
GSTP1Platinum CompoundsOncologyC/D2A
HAS3DaunorubicinCerubidineOncologyD2B
HAS3DoxorubicinAdriamycin, RobexOncologyD2B
HAS3EpirubicinEllenceOncologyD2B
HAS3IdarubicinIdamycin PFSOncologyD2B
HAS3MitoxantroneNovantrone, OTN MitoxantroneOncologyD2B
HAS3ValrubicinValstarOncologyD2B
HLA-A
Gene Information >
AllopurinolAloprimRheumatologyB2B
HLA-A
Gene Information >
CarbamazepineCarbatrol, TegretolNeurologyView >A1AActionable PGx
HLA-A
Gene Information >
OxcarbazepineTrileptalNeurologyView >C
HLA-B
Gene Information >
AbacavirZiagen, Trizivir, Epzicom/KivexaInfectious DiseaseView >A1ATesting required
HLA-B
Gene Information >
AllopurinolAloprimRheumatologyView >A1A
HLA-B
Gene Information >
CarbamazepineCarbatrolNeurologyView >A1ATesting required
HLA-B
Gene Information >
CarbimazoleNeo-mercazoleInternalC2A
HLA-B
Gene Information >
DapsoneAczoneInfectious DiseaseC2A
HLA-B
Gene Information >
MethazolamideNeptazaneOphtalmologyC2A
HLA-B
Gene Information >
MethimazoleTapazoleInternalC2A
HLA-B
Gene Information >
NevirapineViramuneInfectious DiseaseC2A
HLA-B
Gene Information >
OxcarbazepineTrileptalNeurologyView >A1ATesting recommended
HLA-B
Gene Information >
PhenytoinDilantinNeurologyView >A1AActionable PGx
HLA-B
Gene Information >
PropylthiouracilPropacilInternalC2A
HLA-CAllopurinolAloprimRheumatologyC2B
HLA-CMethazolamideNeptazaneOphtalmologyC2B
HLA-DPB1AspirinGeneralC2B
HLA-DQA1LapatinibTykerbOncologyC2BActionable PGx
HLA-DRB1NevirapineViramuneInfectious DiseaseC2B
HMGCRAtorvastatinLipitorCardiovascularD2A
HMGCRCerivastatinBaycol, LipobayCardiovascularD2A
HMGCRFluvastatinLescolCardiovascularD2A
HMGCRLovastatinMevacorCardiovascularD2A
HMGCRPitavastatinLivaloCardiovascularD2A
HMGCRPravastatinPravacholCardiovascularD2A
HMGCRRosuvastatinCrestorCardiovascularD2A
HMGCRSimvastatinZocorCardiovascularD2A
HTR1AParoxetinePaxilPsychiatryD2B
HTR2AAgomelatineValdoxan, Melitor, ThymanaxPsychiatryD2B
HTR2AAmaxapineAsendinPsychiatryD2B
HTR2AAmitriptylineElavilPsychiatryD2B
HTR2ABupropionWellbutrinPsychiatryD2B
HTR2ACitalopramCelexaPsychiatryD2B
HTR2AClomipramineAnafranilPsychiatryD2B
HTR2ADesipramineNorpraminPsychiatryD2B
HTR2ADesvenlafaxinePristiqPsychiatryD2B
HTR2ADoxepinSilenor, Zonalon, PrudoxinPsychiatryD2B
HTR2ADuloxetineCymbaltaPsychiatryD2B
HTR2AEscitalopramLexaproPsychiatryD2B
HTR2AFluoxetineProzac, SarafemPsychiatryD2B
HTR2AFluvoxamineLuvoxPsychiatryD2B
HTR2AImipramineTogranilPsychiatryD2B
HTR2AIronPsychiatryD2B
HTR2AIsocarboxazidMarplanPsychiatryD2B
HTR2AL-TryptophanTryptan, AminominePsychiatryD2B
HTR2AMaprotilineLudiomilPsychiatryD2B
HTR2AMianserinTolvonPsychiatryD2B
HTR2AMilnacipranIxel, Savella, Dalcipran, ToledominPsychiatryD2B
HTR2AMinaprineBrantur, CantorPsychiatryD2B
HTR2AMirtazapineRemeronPsychiatryD2B
HTR2AMoclobemideAmira, Aurorix, Clobemix, Depnil, ManerixPsychiatryD2B
HTR2ANefazodoneSerzonePsychiatryD2B
HTR2ANortriptylinePamelorPsychiatryD2B
HTR2AParoxetinePaxilPsychiatryD2B
HTR2APhenelzineNardilPsychiatryD2B
HTR2AProtriptylineVivactilPsychiatryD2B
HTR2AReboxetineEronaxPsychiatryD2B
HTR2ASertralineZoloftPsychiatryD2B
HTR2ATranycypromineParnatePsychiatryD2B
HTR2ATrazodoneDesyrelPsychiatryD2B
HTR2ATrimipramineSurmontilPsychiatryD2B
HTR2AVenlafaxineEffexorPsychiatryD2B
HTR2CClozapineClozarilPsychiatryD2B
HTR2COlanzapineZydisPsychiatryD2B
HTR2CRisperidoneRisperdalPsychiatryD2B
IFNL3
Gene Information >
Peginterferon Alfa-2APegasys, Pegasys ProClickGastroenterologyView >A1A
IFNL3
Gene Information >
Peginterferon Alfa-2BPEG-Intron, PEG Intron, SylatronGastroenterologyView >A1AActionable PGx
IFNL3
Gene Information >
RibavirinVirazole, Rebetol, CopegusInfectious DiseaseView >A1A
IFNL4Peginterferon Alfa-2APegasys, Pegasys ProClickGastroenterologyD1A
IFNL4Peginterferon Alfa-2BPEG-Intron, PEG Intron RP, SylatronGastroenterologyD1A
ITPAInterferon Alfa-2BIntron AInfectious DiseaseC/D2B
KCNIP4BenazeprilLotensinCardiovascularD3
KCNIP4CaptoprilAcediur, Aceplus, Acepress, Acepril, Alopresin, Apopril, Capoten, Captolane, Captoril, Cesplon, Dilabar, Garranil, Hipertil, Hypertil, Lopirin, Lopril, Tenosbon, Tensobon, TensoprelCardiovascularD3
KCNIP4EnalaprilVasotecCardiovascularD3
KCNIP4Fosinopril Acecor, Monopril, Secorvas, StarilCardiovascularD3
KCNIP4LisinoprilPrinivil, ZestrilCardiovascularD3
KCNIP4MoexiprilUnivascCardiovascularD3
KCNIP4PerindoprilAceonCardiovascularD3
KCNIP4QuinaprilAccuprilCardiovascularD3
KCNIP4RamiprilAltaceCardiovascularD3
KCNIP4TrandolaprilMavikCardiovascularD3
KIF6AtorvastatinLipitorCardiovascularD2B
KIF6PravastatinPravacholCardiovascularD2B
LDLRAtorvastatinLipitorCardiovascularDInformative PGx
LPAAtorvastatinLipitorCardiovascularD2B
LPACerivastatinBaycol, LipobayCardiovascularD2B
LPAFluvastatinLescolCardiovascularD2B
LPALovastatinMevacorCardiovascularD2B
LPAPitavastatinLivaloCardiovascularD2B
LPAPravastatinPravacholCardiovascularD2B
LPARosuvastatinCrestorCardiovascularD2B
LPASimvastatinZocorCardiovascularD2B
LTC4SAspirinGeneralD2B
MC4RAmisulprideSolianPsychiatryC2B
MC4RAripiprazoleAbilify PsychiatryC2B
MC4RClozapineClozarilPsychiatryC2B
MC4RHaloperidolHaldol PsychiatryC2B
MC4ROlanzapineZyprexaPsychiatryC2B
MC4RPaliperidoneInvegaPsychiatryC2B
MC4RQuetiapineSeroquelPsychiatryC2B
MC4RRisperidoneRisperdalPsychiatryC2B
MC4RZiprasidoneGeodon PsychiatryC2B
MT-RNR1AmikacinAmikinInfectious DiseaseA/B1B
MT-RNR1GentamicinGaramycinInfectious DiseaseA/B1B
MT-RNR1KanamycinKantrexInfectious DiseaseA/B1B
MT-RNR1NeomycinNeo-FradinInfectious DiseaseA/B1B
MT-RNR1StreptomycinInfectious DiseaseA/B1B
MT-RNR1TobramycinTobi, Tobrex, Tobi PodhalerInfectious DiseaseA/B1B
MTHFRCapecitabineXelodaOncologyC3
MTHFRCarboplatinParaplatin OncologyC2A
MTHFRCyclophosphamideCytoxan, NeosarImmunosuppressionC
MTHFRFluorouracilEfudex, Fluoroplex, CaracOncologyC3
MTHFRLeucovorinOncologyC3
MTHFRMethotrexateRheumatrexOncologyC2A
MTHFROxaliplatinEloxatinOncologyC3
MTRRMethotrexateRheumatrexOncologyD2B
NAT1HydralazineApresolineCardiovascularD
NAT1Isosorbide DinitrateIsordil, Isordil Titradose, Dilatrate-SR, SorbitrateCardiovascularD
NAT2HydralazineApresolineCardiovascularD3
NAT2IsoniazidInfectious DiseaseC2A
NAT2Isosorbide DinitrateIsordil, Isordil Titradose, Dilatrate-SR, SorbitrateCardiovascularD
NEDD4LHydrochlorothiazideAquazide H, Hydrocot, Microzide, ZideCardiovascularD2B
NQO1BusulfanBusulfex, MyleranOncologyD2A
NQO1CarmustineBicnu, Gliadel WaferOncologyD2A
NQO1ChlorambucilLeukeranOncologyD2A
NQO1CyclophosphamideCytoxan, NeosarOncologyD2A
NQO1DacarbazineDTIC-DomeOncologyD2A
NQO1DaunorubicinCerubidineOncologyD2A
NQO1DoxorubicinAdriamycin, RubexOncologyD2A
NQO1EpirubicinEllenceOncologyD2A
NQO1FluorouracilEfudex, Fluroplex, Carac, Adrucil, TolakOncologyD2A
NQO1IdarubicinIdamycin PFSOncologyD2A
NQO1IfosfamideIfexOncologyD2A
NQO1LomustineGleostineOncologyD2A
NQO1MechlorethamineMustargen, ValchlorOncologyD2A
NQO1MelphalanEvomelaOncologyD2A
NQO1MitoxantroneNovantrone, OTN MitoxantroneOncologyD2A
NQO1PipobromanVercite, VercyteOncologyD2A
NQO1Platinum CompoundsOncologyD2A
NQO1StreptozocinZanosarOncologyD2A
NQO1TemozolomideTemodar, Temodal, TemcadOncologyD2A
NQO1ThiotepaTepadinaOncologyD2A
NQO1ValrubicinValstarOncologyD2A
NT5C2GemcitabineGemzarOncologyD2B
NUDT15
Gene Information >
AzathioprineAzasanImmunosuppressionView >A
NUDT15
Gene Information >
MercaptopurinePurixanOncologyView >ATesting recommended
NUDT15
Gene Information >
ThioguanineTabloidOncologyView >ATesting recommended
OPRM1AlfentanilAlfentaAnalgesic / AnesthesiologyC/D2B
OPRM1EthanolGeneralC/D2B
OPRM1FentanylDuragesic, SublimazeAnalgesic / AnesthesiologyC/D2B
OPRM1MethadoneDolophine, MethadoseAnalgesic / AnesthesiologyC/D3
OPRM1MorphineKadian, MS ContinAnalgesic / AnesthesiologyC/D2B
OPRM1NaloxoneEvzio, NarcanEmergencyC/D2B
OPRM1NaltrexoneVivitrol, ReviaPsychiatryC/D3
OPRM1TramadolUltram, ConzipAnalgesic / AnesthesiologyC/D2B
OTCValproic AcidValproicNeurologyBActionable PGx
POLGDivalproex SodiumDepakoteNeurologyBTesting required
POLGValproic AcidValproicNeurologyB3Testing required
PRKCAHydrochlorothiazideAquazide H, Hydrocot, Microzide, ZideCardiovascularD2B
PROCWarfarinCoumadin, JantovenAnticoagulant / AntiplateletDActionable PGx
PROS1WarfarinCoumadin, JantovenAnticoagulant / AntiplateletDActionable PGx
PTGFRLatanoprostXalatanOphtalmologyD2B
PTGS1AspirinGeneralD2B
RYR1
Gene Information >
DesfluraneSupraneAnalgesic / AnesthesiologyView >A1AActionable PGx
RYR1
Gene Information >
EnfluraneEthraneAnalgesic / AnesthesiologyView >A1AActionable PGx
RYR1
Gene Information >
HalothaneFluothaneAnalgesic / AnesthesiologyView >A1A
RYR1
Gene Information >
IsofluraneForane, TerrellAnalgesic / AnesthesiologyView >A1AActionable PGx
RYR1
Gene Information >
MethoxyfluranePenthroxAnalgesic / AnesthesiologyView >A1A
RYR1
Gene Information >
SevofluraneUltaneAnalgesic / AnesthesiologyView >A1AActionable PGx
RYR1
Gene Information >
SuccinylcholineAnectine, QuelicinAnalgesic / AnesthesiologyView >A1AActionable PGx
SCN1ACarbamazepineCarbatrolNeurologyB2B
SCN1APhenytoinDilantinNeurologyB2B
SEMA3CIrinotecanCamptosarOncologyD2B
SLC28A3DaunorubicinCerubidineOncologyD2B
SLC28A3DoxorubicinAdriamycin , RubexOncologyD2B
SLC28A3EpirubicinEllenceOncologyD2B
SLC28A3IdarubicinIdamycin PFSOncologyD2B
SLC28A3MitoxantroneNovantrone, OTN MitoxantroneOncologyD2B
SLC28A3ValrubicinValstarOncologyD2B
SLC47A2MetforminFortamet, Glucophase, Glucophase Xr, Glumetza, RiometEndocrinologyD3
SLC6A4CitalopramCelexaPsychiatryB/C2A
SLC6A4EscitalopramLexaproPsychiatryB/C2A
SLCO1B1
Gene Information >
CerivastatinBaycol, LipobayCardiovascularB2A
SLCO1B1
Gene Information >
MethotrexateRheumatrexOncologyC2A
SLCO1B1
Gene Information >
PravastatinPravacholCardiovascularC2A
SLCO1B1
Gene Information >
RosuvastatinCrestorCardiovascularC2AActionable PGx
SLCO1B1
Gene Information >
SimvastatinZocorCardiovascularView >A1AInformative PGx
SOD2CyclophosphamideCytoxan, NeosarOncologyD2B
TANC1RadiotherapyOncologyD2B
TCF7L2SulfonamidesBleph-10, Ocu-Sul, SOSS, Sodlium Sulamyd, Sulf-10, Ocu-Sul, SOSS, Sodium Sulamyd, Sulf-10Infectious DiseaseD
TNFAdalimumabHumiraRheumatologyC2B
TNFEtanerceptEnbrelRheumatologyC2B
TNFInfliximabRamicadeRheumatologyC2B
TP53CisplatinPlatinol, Platinol-AQOncologyD
TP53CyclophosphamideCytoxan, NeosarOncologyD3
TPMT
Gene Information >
AzathioprineAzasanImmunosuppressionView >A1ATesting recommended
TPMT
Gene Information >
MercaptopurinePurixanOncologyView >A1ATesting recommended
TPMT
Gene Information >
ThioguanineTabloidOncologyView >A1ATesting recommended
TXNRD2CitalopramCelexaPsychiatryD2B
TXNRD2EscitalopramLexaproPsychiatryD2B
TXNRD2FluoxetineProzac, SarafemPsychiatryD2B
TXNRD2FluvoxamineLuvoxPsychiatryD2B
TXNRD2ParaxetinePaxil, PexevaPsychiatryD2B
TXNRD2SertralineZoloftPsychiatryD2B
TYMSCapecitabineXelodaOncologyD2A
TYMSFluorouracilEfudex, Fluroplex, Carac, Adrucil, TolakOncologyD2A
UGT1A1
Gene Information >
AtazanavirReyatazInfectious DiseaseView >A1A
UGT1A1
Gene Information >
BelinostatBeleodaqOncologyB3Actionable PGx
UGT1A1
Gene Information >
DolutegravirTivicayInfectious DiseaseB/CActionable PGx
UGT1A1
Gene Information >
IrinotecanCamptosarOncologyA2AActionable PGx
UGT1A1
Gene Information >
NilotinibTasignaOncologyC3Actionable PGx
UGT1A1
Gene Information >
PazopanibVotrientOncologyB/C3Actionable PGx
UGT1A4LamotrigineLamictalNeurologyD2B
UGT2B15OxazepamSeraxPsychiatryD2B
UMPSFluorouracilEfudex, Fluroplex, Carac, Adrucil, TolakOncologyD2B
VDRPeginterferon Alfa-2BPEG-Intron, PEG Intron RP, SylatronGastroenterologyD2A
VDRRibavirinVirazole, Rebetol, CopegusGastroenterologyD2A
VKORC1
Gene Information >
WarfarinCoumadin, JantovenAnticoagulant / AntiplateletView >A1AActionable PGx
XPCCisplatinPlatinol, Platinol-AQOncologyC1B
XRCC1PlatinumOncologyD
YEATS4HydrochlorothiazideAquazide H, Hydrocot, Microzide, ZideCardiovascularD2B

Learn more about the genes

Clinic here to learn more about the WPS genes that have CPIC guidelines.

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Disclaimer

*The WPS gene-drug database is created based on the Clinical Pharmacogenomics Implementation Consortium (CPIC) Gene-Drug table. Please be noted that only the genes tested by WPS are shown in the database.

According to CPIC, “only CPIC level A and B gene/drug pairs have sufficient evidence for at least one prescribing action to be recommended. CPIC level C and D gene/drug pairs are not considered to have adequate evidence or actionability to have prescribing recommendations”. However, “the levels (A, B, C, and D) assigned are subject to change. Only those gene/drug pairs that have been the subject of guidelines have had sufficient in-depth review of evidence to provide definitive CPIC level assignments.”

Please return and check the database regularly for the latest updates on the gene-drug information.

-Date last updated: July 15, 2019-